Genetics of Male Infertility

Genetics of Male Infertility

This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.


Author
Publisher Springer Nature
Release Date
ISBN 3030379728
Pages 375 pages
Genetics of Male Infertility
Language: en
Pages: 375
Authors: Mohamed Arafa
Categories: Health & Fitness
Type: BOOK - Published: 2020-03-14 - Publisher: Springer Nature

This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In additio
The Genetics of Male Infertility
Language: en
Pages: 337
Authors: Douglas T. Carrell
Categories: Medical
Type: BOOK - Published: 2007-11-08 - Publisher: Springer Science & Business Media

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the
The Genetic Basis of Male Infertility
Language: en
Pages: 306
Authors: Ken McElreavey
Categories: Medical
Type: BOOK - Published: 2012-11-03 - Publisher: Springer Science & Business Media

Every year there are new and exciting developments in assisted human reproduction, but how much do we really know about the underlying causes of infertility? Th
Genetics of male infertility
Language: en
Pages: 132
Authors:
Categories:
Type: BOOK - Published: 2007* - Publisher:

Male Fertility and Infertility
Language: en
Pages:
Authors: T. D. Glover
Categories: Medical
Type: BOOK - Published: 2009-03-19 - Publisher: Cambridge University Press

This contemporary account of male fertility provides a much needed bridge between those seeking to understand the subject from an evolutionary and biological pe
Genetics of male infertility
Language: en
Pages: 132
Authors:
Categories:
Type: BOOK - Published: 2007 - Publisher:

Genetics of Human Infertility
Language: en
Pages: 178
Authors: P.H. Vogt
Categories: Medical
Type: BOOK - Published: 2017-09-12 - Publisher: Karger Medical and Scientific Publishers

Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its c
Genetics of male infertility
Language: en
Pages: 132
Authors:
Categories:
Type: BOOK - Published: 2007* - Publisher:

Male Infertility: Understanding, Causes and Treatment
Language: en
Pages: 497
Authors: RAJENDER SINGH
Categories: Medical
Type: BOOK - Published: 2017-06-17 - Publisher: Springer

This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and trea
Monothematic Issue: Genetics of Male Infertility
Language: en
Pages: 73
Authors: C. Foresta
Categories:
Type: BOOK - Published: 2000 - Publisher: