Red Blood Cell Aggregation

Red Blood Cell Aggregation

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.


Author
Publisher CRC Press
Release Date
ISBN 1439841802
Pages 326 pages
Red Blood Cell Aggregation
Language: en
Pages: 326
Authors: Oguz Baskurt
Categories: Medical
Type: BOOK - Published: 2011-09-28 - Publisher: CRC Press

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coi
Handbook of Hemorheology and Hemodynamics
Language: en
Pages: 468
Authors: O.K. Baskurt
Categories: Medical
Type: BOOK - Published: 2007-10-03 - Publisher: IOS Press

This publication primarily focuses on the macro- and micro-rheological behavior of blood and its formed elements, on interactions between the formed elements an
Red Blood Cell Aggregation
Language: en
Pages: 318
Authors: Oguz Baskurt
Categories: Medical
Type: BOOK - Published: 2011-09-28 - Publisher: CRC Press

Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coi
Dynamics of Blood Cell Suspensions in Microflows
Language: en
Pages: 476
Authors: Annie Viallat
Categories: Medical
Type: BOOK - Published: 2019-12-09 - Publisher: CRC Press

Blood microcirculation is essential to our bodies for the successful supply of nutrients, waste removal, oxygen delivery, homeostasis, controlling temperature,
Clinical Hemorheology
Language: en
Pages: 398
Authors:
Categories: Blood
Type: BOOK - Published: 1990 - Publisher:

Handbook of Hemorheology and Hemodynamics
Language: en
Pages: 469
Authors: Oguz K. Baskurt
Categories: Medical
Type: BOOK - Published: 2007 - Publisher: IOS Press

" This publication primarily focuses on the macro- and micro- rheological behavior of blood and its formed elements, on interactions between the formed elements
Red Blood Cells at the Mount of Truth: Highlights of the 22nd Meeting of the European Red Cell Research Society
Language: en
Pages: 144
Authors: Anna Bogdanova
Categories: Science
Type: BOOK - Published: 2021-01-06 - Publisher: Frontiers Media SA

The Red Blood Cell
Language: en
Pages: 782
Authors: Douglas MacN. Surgenor
Categories: Medical
Type: BOOK - Published: 2013-10-22 - Publisher: Academic Press

The Red Blood Cell, Second Edition, Volume II provides a comprehensive treatment and review of basic biomedical knowledge about the circulating, adult red blood
Depletant Induced Attractions in Red Blood Cells
Language: en
Pages: 0
Authors: Austin Nehring
Categories:
Type: BOOK - Published: 2018 - Publisher:

Red blood cells suspended in plasma are able to aggregate into linearly stacked rouleau. The aggregations can form complex clusters and branching networks which
Hemorheology in Practice
Language: en
Pages: 142
Authors: J. F. Stoltz
Categories: Medical
Type: BOOK - Published: 1999 - Publisher: IOS Press

Haemorheology is the study of how the blood, the blood cells and the vessels can function and interact as parts of the living organism. It is presented in this